Management of Perioperative Anticoagulation in a Patient with Antiphospholipid Antibody Syndrome Undergoing Cardiac Surgery: A Case Report

Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.

Keywords

Antifibrinolytics, antiphospholipid syndrome, cardiopulmonary bypass, immune thrombocytopenic purpura, Libman?Sacks endocarditis

Citation

Malviya Sanjana A, Deng Yi, Gilani Sayyed O, Hendon Alec A, Nikolaidis Melissa A, Moseley Micah S.. Management of Perioperative Anticoagulation in a Patient with Antiphospholipid Antibody Syndrome Undergoing Cardiac Surgery: A Case Report. Annals of Cardiac Anaesthesia. 2022 Jun; 25(2): 206-209

URI

https://imsear.searo.who.int/handle/123456789/219210

Collections

Annals of Cardiac Anaesthesia

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