Prevalence and Determinants of HIV Related Eye in Patients Attending Anti-retroviral Therapy Clinic in Katsina State, Nigeria

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Date
2023-01
Journal Title
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Publisher
Sciencedomain International
Abstract
Background: HIV and its complication AIDS was a source of serious public health concern that greeted the end of the 20th century. Being a multi-systemic disease, it was also associated with different forms of ocular morbidities of interest. Purpose: To determine the prevalence, patterns and determinants of HIV related eye diseases in patients attending anti-retroviral clinics in Katsina state, Nigeria.Methods: Two hundred and twenty subjects met the inclusion criteria over a six month period. A questionnaire was administered for socio-demographic data, patients’ history, record review and a detailed ophthalmic examination. Data was analysed using SPSS version 20. Parametric and non-parametric assessments were used to assess the relationship of various factors with manifestation of HIV associated eye diseases.Results: Out of 220 respondents, 164 were females. The Male: Female was 1:2.9. The mean age was 28.5 years ± 14.83 SD. About 65.5% of respondents had eye diseases while 46.4% had HIV associated eye diseases. Prevalence of HIV associated eye diseases was found to be 46.4%. The most common types of eye diseases found were Kerato-conjunctivitis Sicca (KCS) 25.5%, conjunctivitis 5.5%, herpes zoster ophthalmicus 3.2%, anterior uveitis 2.7% and molluscum contagiosum 2.3%. Factors found to affect the manifestation of these eye diseases were CD4 cell count, WHO Clinical Stage of the disease and the Presence of eye symptoms.Conclusion: The study showed a high prevalence of HIV associated eye disease. The Patient’s clinical/WHO stage, CD4 cell count and presence of ocular symptoms were shown to have significant association with the ocular manifestation.
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Keywords
Prevalence, determinants, HIV related eye diseases, ocular manifestations, Katsina
Citation
Halima A, Eze U. A, Suleiman Y. S, Aba E. R, Samaila E.. Prevalence and Determinants of HIV Related Eye in Patients Attending Anti-retroviral Therapy Clinic in Katsina State, Nigeria. Ophthalmology Research: An International Journal. 2023 Jan; 18(1): 45-55