Prevalence of Drug Interactions and Potentially Inappropriate Medications Among Geriatric Patients in India.
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Date
2022-12
Journal Title
Journal ISSN
Volume Title
Publisher
Light House Polyclinic
Abstract
Aim: The study aimed to determine the prevalence of potential drug-drug interactions (PDDIs) and potentially inappropriate medications (PIMs) among geriatrics. Methods: A prospective observational study was conducted for six months in the Department of Geriatrics, M.S. Ramaiah Teaching Hospital, Bangalore. PDDIs and PIMS were analyzed using micromedex database and Beer's criteria respectively. Results: Among 395 prescriptions, 221(56%) prescriptions showed 559 pDDIs and 41(10.4%) PIMs. Almost 281(50.3%), 260(46.5%), 16(2.7%) and 2(0.3%) pDDIs were categorised as major, moderate, minor and contraindicated respectively. Almost 321(57.5%) were synergistic and 196(35.0%) were antagonistic drug interactions. Pearson correlation value (R) is 0.9957 which showed a strong positive correlation. Conclusion: This study created awareness on drug interactions among geriatrics and help the practitioners to prescribe drugs with a low risk of pDDIs. The authors suggest PIM monitoring in geriatrics to avoid adverse effects and improve patients' quality of life.
Description
Keywords
Adverse effects, Beer's criteria, Geriatrics, Potential Drug-Drug Interactions, Potentially Inappropriate Medications.
Citation
Yoganna PN, Sandra A, Bachol K, Maheswari E, Aruna Sree P.. Prevalence of Drug Interactions and Potentially Inappropriate Medications Among Geriatric Patients in India.. Light House Polyclinic. 2022 Dec; 21(4): 1-5