Renal-limited systemic lupus erythematosus: Avoiding delay in diagnosis
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Date
2023-01
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer – Medknow
Abstract
Nephrotic syndrome (NS) and glomerulonephritis (GN) are disorders of varied etiologies. Systemic lupus erythematosus (SLE) is one of the multisystemic diseases causing NS and GN. SLE is often suspected whenever NS/GN is associated with extrarenal manifestations. However, it presents solely as NS or GN without extrarenal features in a handful of cases. This affects the prognosis adversely as negligent delay in diagnosis of SLE and initiation of immunosuppressive therapy is associated with poorer response. We present a series of five women who presented solely with renal manifestations. The diagnosis of SLE was delayed, as the women did not have any extrarenal features. We started immunosuppressive therapy after a diagnosis of lupus nephritis was made in retrospect after a kidney biopsy. This case series highlights the importance of performing serology tests for SLE in all young female patients who present with NS/GN to avoid delay in diagnosis.
Description
Keywords
Delay, diagnosis, lupus-nephritis, renal-limited, systemic lupus erythematosus
Citation
Kaur Inderjot, Nayak Aditya, Kejriwal Amrit. Renal-limited systemic lupus erythematosus: Avoiding delay in diagnosis. MGM Journal of Medical Sciences. 2023 Jan; 10(1): 149-151