Super Porous Hydrogels: A Review
Loading...
Date
2020-08
Journal Title
Journal ISSN
Volume Title
Publisher
SCIENCEDOMAIN international
Abstract
Super porous hydrogels (SPHs) basically developed initially create as a novel drug delivery system to absorb and continue to hold the drugs in the gastric medium which allows absorption in stomach and upper part of the gastrointestinal tract. These systems get swollen in the stomach instantly and in the harsh stomach environment they maintain their integrity, while the pharmaceutical active ingredient is being released. Instant and fast swelling property of hydrogel is based on water absorption through open porous structure by capillary force. SPHs have the poor mechanical strength which has got over by developing the second-generation SPH composites (SPHCs) and the third-generation SPH hybrids (SPHHs). The present review has been focused on the preparation, characterization and application of SPHs
Description
Keywords
Super porous hydrogels, gastric retention, absorption window, second and third generation SPH
Citation
Kumari P. V. Kamala, Sharmila M., Rao Y. Srinivasa. Super Porous Hydrogels: A Review. Journal of Pharmaceutical Research International. 2020 Aug; 32(13): 153-165