Phenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'s
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Date
2020-06
Journal Title
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Publisher
SCIENCEDOMAIN international
Abstract
Barbareagenus has been presented about 12 species, 9 taxon are endemic, in Turkey. In this sudy, enzyme inhibition was carried out on methanolic extract, chloroform extract, ethyl acetate extract, and the remaining aqueous phases from the aerial parts of B. auriculata var paludosa, B. integrifolia, andB. plantagineaspecies and HPLC studies were carried on their methanolic extract in the present study for the first time. Phenolic compounds were determined using reverse phase-high performance liquid chromatography (RP-HPLC). p-OH benzoic acid, vanilic acid, syringaldehyde, coumaric acid, synapic acid and benzoic acid were detected as major phenolic compounds in the species. Assay of enzyme inhibition activitieswere done using spectrophotometric methods. Results of these studies reveal that the extracts from these species have moderate tyrosinase, AChE and BuChE inhibitory activity. In the biological activity studies, it was observed that B. integrifoliawas thehighest activity
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Keywords
Barbarea, brassicaceae, enzyme ınhibition, phytochemical
Citation
Badem Merve, Sener Sıla Ozlem, Korkmaz Nuriye, Kanbolat Seyda, Yildirmiş Sermet, Ozgen Ufuk, Aliyazicioglu Rezzan, Kandemir Ali. Phenolic Content and Enzyme Inhibition Activities Barbarea auriculata var. paludosa, B. integrifolia and B. plantaginea (Brassicaceae)'s. Journal of Pharmaceutical Research International. 2020 Jun; 32(9): 86-93