Michelia champaca L. Derived Phytochemicals against Peptidase Do of Bordetella pertussis Causing Cough
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Date
2020-06
Journal Title
Journal ISSN
Volume Title
Publisher
SCIENCEDOMAIN international
Abstract
Phytochemicals from Michelia champaca L. plant extract are traditionally used to cure cough. Cough can be caused by many reasons. Caugh can be caused by the infection of Bordetella pertussis. The objective of the study is to identify the phytochemical of Michelia champaca capable of curing cough. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that magnoflorine can effectively deactivate the peptidase Do enzyme which will interrupt the life cycle of the microorganism and inhibit the multiplication
Description
Keywords
Phytochemical, Michelia champaca, Bordetella pertussis, cough
Citation
Dash Sanjeeb Kumar, Ray Sidhartha, Behera Smruti Ranjan, Jal Soumya, Bhattacharyay Dipankar. Michelia champaca L. Derived Phytochemicals against Peptidase Do of Bordetella pertussis Causing Cough. Journal of Pharmaceutical Research International. 2020 Jun; 32(8): 133-135