Invitro drug sensitivity of Trichophyton species against griseofulvin and ketoconazole.

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2002-02-06
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Abstract
The in vitro activity of griseofulvin and ketoconazole was investigated against Trichophyton mentagrophytes (Robin) Blanchard and T. Simii (Pinoy) Stockdale, Mackenzie and Austwick. A gradual decrease in growth was observed with increase in concentration of both antibiotics. Ketoconazole was the more effective antibiotic than griseofulvin as it observed to inhibit > 50% mycelial weight even at a lower concentration of 100 ppm. While griseofulvin was effective to cause > 50% growth inhibition only at higher dosage of 400 ppm.
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Dodia S, Bajpai R, Singh BG. Invitro drug sensitivity of Trichophyton species against griseofulvin and ketoconazole. Hindustan Antibiotics Bulletin. 2002 Feb-Nov; 44(1-4): 47-8