A Histomorphological Study of Nephrectomy Specimens in Rural Rajasthan- A Population Based Study.
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Date
2020-08
Journal Title
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Publisher
Akshantala Enterprises Private Limited
Abstract
Nephrectomy brings in relief to patients from various chronic and life threatening diseases and in some cases makes way for renal transplant. Renal cell carcinoma accounts for 3% of all cancer deaths. Staging and grading remain the most useful indicators. Hence the present study was undertaken to become familiar with the morphological features and to explore, elucidate and document the kidney lesions at nephrectomy. We wanted to study the spectrum of renal lesions post nephrectomy, obtain the overall frequency, the age and sex incidence of various lesions at nephrectomy along with detailed histomorphology study of various lesions encountered in nephrectomy specimens and evaluate the histomorphological study of renal tumours including the classification of cell type, architectural pattern and grading. MethodsThis prospective study was done on 85 nephrectomy specimens received in the department of pathology, N.I.M.S. Medical College, Jaipur, over a period of three years (2016 to 2019). ResultsOf these 85 nephrectomy specimens, 44 cases (51.7%) were neoplastic and remaining 41 cases (48.2%) were non-neoplastic. ConclusionsThe youngest patient was 40 days and oldest was 75 years. Chronic pyelonephritis was the commonest non-neoplastic lesion. Renal cell carcinoma was the commonest tumour and was commoner in males with clear cell variant being the most frequent. Monophasic Wilms tumour was the commonest neoplastic lesion in the paediatric population.
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Keywords
Nephrectomy, Chronic Pyelonephritis, Renal Cell Carcinoma
Citation
Gupta Sumit, Sankhala Kalpana, Sanwalka Madhvi, Khatri Jyotsana, Kumar Deepak. A Histomorphological Study of Nephrectomy Specimens in Rural Rajasthan- A Population Based Study.. Journal of Evolution of Medical and Dental Sciences. 2020 Aug; 9(31): 2181-2186