Phase-separation in chromatin organization
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Date
2020-01
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Academy of Sciences
Abstract
The organization of chromatin into different types of compact versus open states provides a means to fine tune generegulation. Recent studies have suggested a role for phase-separation in chromatin compaction, raising new possibilities for regulating chromatin compartments. This perspective discusses some specific molecular mechanismsthat could leverage such phase-separation processes to control the functions and organization of chromatin
Description
Keywords
Histone, nucleosome, heterochromatin, phase-separation, auto-inhibition
Citation
Narlikar Geeta J. Phase-separation in chromatin organization. Journal of Biosciences. 2020 Jan; : 1-5