Microfilariae in bone marrow aspirate of a case of myelofibrosis: A cause or coincidence?
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Date
2020-04
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer India Pvt. Ltd.
Abstract
Filariasis is among the common parasitic infestations found in India, with Wuchereria bancrofti being the most common causative organism. Presentation ranges from clinically asymptomatic to profound elephantiasis. It is also detected incidentally in diagnostic samples such as body fluids, fine needle aspirates, peripheral blood smears, and other cytological smears. Its detection in bone marrow aspirates with an associated hematolymphoid neoplasm is rare, with only a few case reports. We report one such case of young male who presented with leukocytosis of 253 × 109/L with basophilia and massive splenomegaly. Bone marrow aspirate smears showed the presence of microfilariae along with other features of a myeloproliferative neoplasm (MPN). The present case is probably the first case of finding a microfilaria in a case of MPN
Description
Keywords
Bone marrow fibrosis, microfilariae, myeloproliferative neoplasm
Citation
Khaliqur Rahman, Shivangi Harankhedkar, Gupta Ruchi, Gupta Tanvi, Sharma Seema, Nityanand Soniya. Microfilariae in bone marrow aspirate of a case of myelofibrosis: A cause or coincidence?. Journal of Cancer Research and Therapeutics. 2020 Apr; 16(1): 164-166