Molecular characterization of metastasizing ameloblastoma: A comprehensive review

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Date
2019-05
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer India Pvt. Ltd.
Abstract
Metastasizing ameloblastoma (MA) is a very rare odontogenic tumor with 2% of incidence rate. It exhibits benign histopathological features and malignant intrinsic quality in the form of metastasis which makes it a little more than a pathological curiosity. Various molecular aspects related with malignant behavior have been discussed. Because of this, it provides a diagnostic challenge for clinicians and surgeons. It is an elusive lesion which should be more researched and studied so that definitive diagnostic features can be put forward. The objective of this paper is to review the molecular aspect involved in the pathogenesis of MA which will aid in differentiating non-MA from MA and thus helping in providing proper treatment at an early stage
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Keywords
Metastasizing ameloblastoma, nonmetastasizing ameloblastoma, odontogenic tumor
Citation
Ganjre Anjali P, Sarode Gargi, Sarode Sachin. Molecular characterization of metastasizing ameloblastoma: A comprehensive review. Journal of Cancer Research and Therapeutics. 2019 May; 15(3): 455-462