A rare case: Branch retinal vein occlusion associated with the use of tamoxifen

Tamoxifen-induced ocular complications including cataracts, keratopathies, retinopathy, impaired visual acuity, ocular irritation, optical neuritis, and retinal vein occlusion are uncommonly reported in the literature. Herein, we report on a premenopausal patient with right-side breast carcinoma who received adjuvant tamoxifen therapy (20 mg/day) for 1.5 years and developed sudden visual loss. Fundal examination revealed an obstruction in the branch of the retinal vein. The diagnosis was confirmed by fluorescein angiography and optical coherence tomography. Thus, tamoxifen was switched to an aromatase inhibitor. Tamoxifen-induced ocular complications should be kept in mind when visual symptoms are seen in patients undergoing tamoxifen therapy. In such cases, a complete ocular examination should be performed

Keywords

Breast cancer, ocular toxicity, retinal vein occlusion, tamoxifen therapy

Citation

Demirci Nebi Serkan, Erdem Gokmen Umut, Uçgun Nil İrem, Bozkaya Yakup, Ozdemir Nuriye Yildirim, Dogan Mutlu, Zengin Nurullah. A rare case: Branch retinal vein occlusion associated with the use of tamoxifen. Journal of Cancer Research and Therapeutics. 2019 May; 15(3): 722-724

URI

https://imsear.searo.who.int/handle/123456789/213417

Collections

Journal of Cancer Research and Therapeutics

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