Evaluate the differences in serum magnesium levels and lipid profile with correlation of hemoglobin A1C levels in type 2 diabetes patients: a case control study
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Date
2019-10
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Background: Magnesium deficiency is a common problem in diabetic patients. Magnesium deficiency may increase the incidence of Type 2 Diabetic (T2D) and occurrence complications. Objective of this study aimed at determining the differences in serum magnesium levels and lipid profile among patients newly diagnosed with T2D and normoglycemic individuals.Methods: The cross sectional observation study design was conducted at Sri Aurobindo Medical College, from March 2018 to April 2019. Source populations were all patients who attending to the OPD, Department of General Medicine. A total of 75 patients were enrolled in this study. This study was divided in two group’s cases group (T2D) and second control group (Non-diabetic). First group not initiated on any oral-hypoglycaemic, anti-hypertensive or lipid lowering drugs, and healthy patients were included in control group.Results: Triglycerides (TG), Total Cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) showed significantly (p<0.001) higher mean levels in T2D compared to the controls. The Magnesium and High-Density Lipoproteins-cholesterol (HDL-C) levels were significantly (p<0.001) lower among the T2D group compared to the control group. There was a significant inverse correlation (r2= 0.567, p<0.001) between Hemoglobin A1C (HbA1c) levels and serum magnesium.Conclusions: Serum magnesium levels and lipid profile were significantly different in T2D patients compared to control group.
Description
Keywords
Hemoglobin A1C, Lipid profile, Serum magnesium, Type 2 diabetes
Citation
Gupta B.B., Vaidya S.A., Bhandari Mahak, Behl Simran, Kosta Susmit. Evaluate the differences in serum magnesium levels and lipid profile with correlation of hemoglobin A1C levels in type 2 diabetes patients: a case control study. International Journal of Research in Medical Sciences. 2019 Oct; 7(10): 3874-3877