Echocardiographic Findings In Thalassemia Major Patients: An Experience From Jammu
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Date
2019-01
Journal Title
Journal ISSN
Volume Title
Publisher
JK Science
Abstract
Current Study was done to assess the echocardigraphic changes in Thalassemia Major patients. All
Thalassemic Major patients above 10 years of age registered with Thalassemia day care centre at SMGS
hospital, Government Medical College Jammu with normal electrocardiogram and no clinical features of
heart failure were included in this retrospective study. Their medical records were analyzed in terms of
age, gender, average hemoglobin levels, serum ferritin levels and echocardiographic findings. 95 patients
who were more than 10 years of age and had normal electrocardiogram and no clinical features of heart
failure were included in this study. Out of these 95 patients 55 showed abnormal findings on
echocardiography. All patients except one showed normal systolic function. Echocardiography in 54 patients
showed only diastolic dysfunction and one had tricuspid regurgitation (TR) in addition . 55 Thalassemia
major patients with abnormal echocardiographic findings comprised of 30 males and 25 females. All the
patients in the age group of more than 20 years and 12 patients in the age group of 10 years to 20 years
showed abnormal echocardiographic findings. Average hemoglobin and serum ferritin in these children
were around 5-7gms /dl and more than 3000 ng/ml respectively. Echocardiographic findings suggestive of
left ventricular diastolic dysfunction were the commonest findings indicating early cardiac dysfunction in
patients with Thalassemia major in 2nd and 3rd decade of their life.
Description
Keywords
Echocardiography, Thalassemia, Serum Ferritin, Diastolic Dysfunction
Citation
Digra Sanjeev Kumar, Kumar Dharminder, Bhat Sanjeev, Saini Ghan Shyam. Echocardiographic Findings In Thalassemia Major Patients: An Experience From Jammu. JK Science Journal of Medical Education and Research. 2019 Jan; 2019 Jan: 8-10