Chronic Nonhealing Ulcers ‒ Garhwal Region (Etiopathology, Microbiology with Susceptibility, Managements & Outcomes)
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Date
2020-06
Journal Title
Journal ISSN
Volume Title
Publisher
SCIENCEDOMAIN international
Abstract
Introduction:Chronic nonhealing ulcers, with varied etio-pathologies, are difficult to manage and warrant  meticulous,  early  and  prolonged  directed  treatment  to  prevent  their  development  and complications.Methods:Patients of chronic ulcers (>3 months’ duration), having undergone surgical management at our Institute, VCSGGMS&RI-UT, between January 2018 –August 2019, numbering one hundred twenty  five  (N=  125), were  included  in  this  concurrent  observational study,  aimed  at  identifying implicated microrganism(s) and their antibiotic susceptibility, for promoting wound healing, along with surgical measures Results:Male patients (M:F :: 87:38; 69.6% males) in the “20-50 year” age-group (74; 59.2%), with diabetic  ulcers  (35;28.0%),  burns  etc.  (21;16.8%)  and  traumatic  ulcers  (18;14.4%)  etc. predominated  in  the  chronic  non-healing  state.  Gram  positive  (68;  54.4%)  organisms  (including Staphylococcus) were the major isolates from the ulcers; organisms showing higher sensitivity to the newer generations/groups of antibiotics. Uncontrolled Diabetes, other prolonged illnesses &/or under-nutrition  were  important  causative  factors,  requiring  their  remediations  and  also debridements ± skin/flap coverage (45; 36.0%) with prolonged course of antibiotics and occasional amputations (18; 14.4%) for adequate treatment.Conclusion:Skilled intensive multidisciplinary effort is essential to achieve satisfactory healing and prevent disfigurement and to limit disability and death (11; 8.8%) among the patients.
Description
Keywords
Antibiotic sensitivity, bacterial profile, chronic wound, diabetic ulcer, nonhealing ulcers
Citation
Keshri Amit, Bhatt Mukul P., Kumar Santosh, Punita K.. Chronic Nonhealing Ulcers ‒ Garhwal Region (Etiopathology, Microbiology with Susceptibility, Managements & Outcomes). International Journal of TROPICAL DISEASE & Health. 2020 Jun; 41(5): 53-64