Clinical Significance of Neck Dissection in Post-radiotherapy Clinically Negative N0 Neck in Advanced T3/T4 Oral Malignancies

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Date
2019-05
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Journal ISSN
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Publisher
International Research Organization for Life & Health Sciences (IROLHS)
Abstract
Introduction: Optimal therapy for patients with metastatic neck disease remains controversial. Neck dissection followingradiotherapy has, traditionally, been used to improve locoregional control.Aim: The aim of the study was to study the neck dissection in post-RT clinically negative neck (cN0) in advanced T3/T4 oralmalignancies.Materials and Methods: In this retrospective study, cases of oral squamous cell carcinoma were included from 2014 to 2018.The study includes 16 patients with a cN0. Patients with advanced T stage (T3/T4), the presence of lymphovascular invasion,the presence of perineural invasion, positive surgical margins, lymph node involvement, extracapsular nodal extension, andbone involvement were received post-operative radiotherapy (PORT).Results: A total of 16 cases were included in the study, the PORT was given to six patients where three of them were pN+and three were pN0 but had adverse features of primary tumors that mandate PORT. The regional recurrence had occurredin 1 case which was pN+.Conclusion: Tumor recurrence was not influenced statistically with the use of PORT in the cN0.
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Keywords
Clinical negative neck, Elective neck dissections, Neck dissections, Oral cancer, Squamous cell carcinoma
Citation
G Balamurugan, Venkatachalam A Suresh. Clinical Significance of Neck Dissection in Post-radiotherapy Clinically Negative N0 Neck in Advanced T3/T4 Oral Malignancies. International Journal of Scientific Study. 2019 May; 7(1): 201-203