Serum immunoglobulins in minimal change nephrotic syndrome--a possible defect in T-cell function.

Rashid, H; Skillen, A W; Morley, A R; Kerr, D N

Serum immunoglobulins in minimal change nephrotic syndrome--a possible defect in T-cell function.

Date

1982-06-01

Authors

Abstract

Serum immunoglobulin concentrations were determined in eighteen patients with minimal change nephrotic syndrome. Serum IgG and IgA were significantly decreased; whereas IgM was significantly increased in majority of the cases. Eight of the eighteen patients were treated with steroids. All the eight patients showed a significant increase in serum IgG and a decrease in IgM in response to steroid therapy. The increased serum IgM and decreased IgG before treatment and their restoration to normal levels after steroid therapy may suggest a possible defect in T-cell function.

Description

Bangladesh Medical Research Council Bulletin.

Citation

Rashid H, Skillen AW, Morley AR, Kerr DN. Serum immunoglobulins in minimal change nephrotic syndrome--a possible defect in T-cell function. Bangladesh Medical Research Council Bulletin. 1982 Jun; 8(1): 15-20