A prospective observational study on the effect of Erythropoiesis stimulating agents in chronic kidney disease Anemia patients
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Date
2020-09
Journal Title
Journal ISSN
Volume Title
Publisher
Society for research and Development in Education
Abstract
Background and Objectives: Anemia is a frequent complication, and significant morbidity and mortality in patient with chronic kidney disease (CKD). Erythropoiesis Stimulating Agents (ESAs) have become the standard care for anemia t erapy and reduces need for blood transfusions. The bjective of the study was to evaluate the safety and effect of ESAs and to create the awareness among patients regarding the Erythropoiesis stimulating agents through patient i formation leaflets.Methods: The prospective observational study of 6-month duration was conducted in a tertiary care hospital. A total of 162 patients on ESAs were enrolled in the study. Patients were followed for continuously and the mean difference is assessed by monitoring the primary and secondary hematological parameters before and after ESAs administration. Patient information leaflet was given t the patients for education and awareness about ESAs.Results: Out of 162 patients, after the administration of ESAs mean value increase in hemoglobin level was found from base line 6.9g/dL to 11.6g/dL. Significant improvement was noted in CKD anemia patient indicating impact of patient counseli g.Conclusion: It can be concluded that Erythropoiesis Stimulating Agents in treatment of anemia along with effective counseling from clinical pharmacist benefits CKD patients and improves the health outcomes.
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Keywords
Anemia, Blood transfusion, Erythropoietin, Chronic Kidney Disease, Erythropoiesis Stimulating Agents
Citation
Jose Manjumol, Singh Sonia Kumari, Achankunju Vinson, Sundaraswamy Punitha, Sherief Sheik Haja, Thangaval Sivakumar. A prospective observational study on the effect of Erythropoiesis stimulating agents in chronic kidney disease Anemia patients. International Journal of Research and Development in Pharmacy & Life Sciences (IJRDPL). 2020 Sep; 9(1): 7-12