Comparison of the Effectiveness of Bone Marrow Aspiration, Imprint and Biopsy in Patients Suffering From Acute Leukaemia
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Date
2019-11
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Journal ISSN
Volume Title
Publisher
Ibn Sina Academy of Medieval Medicine & Sciences
Abstract
Background: Examination of bone marrow has wideapplications in clinical medicine. Bone marrow can beevaluated by three ways – Bone marrow aspirate (BMA)smears, Imprints or touch preparations (BMI) of bone marrowcore biopsies, and histological sections of core biopsies(BMBx). Hence; we planned the present study to assess andcompare the effectiveness of bone marrow aspiration, imprintand biopsy in patients suffering from acute leukaemia.Materials & Methods: The present study includedcomparative evaluation of efficacy of bone marrow aspiration,imprint and biopsy in acute leukaemia cases. We carried outbone marrow examination on 10 cases presenting with acuteleukaemia’s. We included only those cases in which bonemarrow examination was done by using all the three methodsof BMA, BMI and BMBx will be included in the study. A Salah'sneedle was used to aspirate material from bone marrow.Biopsy was done using a Jamshidi/Janus trephine needle.After routine processing and paraffin embedding thin sectionswere cut and stained with Haematoxylin and Eosin stain. Weanalyzed all the results by SPSS software.Results: Out of 10 cases, findings of BMA, BMI and BMBxwere in concordance with each other in 70 percent of thecases. In two cases, dry tap was observed, which was furtherdiagnosed with BMI and BMBx. Diluted marrow was observedin one case which was further diagnosed with BMI and BMBx.Findings of BMI and BMBx were in concordance with eachother in 100 percent of the cases.Conclusion: All the three diagnostic techniques arecomplementary to each other.
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Keywords
Aspiration, Biopsy, Bone marrow, Imprint
Citation
Yadav Kamlesh, Khinchi Mukesh Kumar. Comparison of the Effectiveness of Bone Marrow Aspiration, Imprint and Biopsy in Patients Suffering From Acute Leukaemia. International Journal of Medical Research Professionals. 2019 Nov; 5(6): 163-166