Acute Hyponatremia And Hypernatremia Related To Intravenous Fluid Administration In Hospitalized Children: A Randomized Observational Study
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Date
2019-04
Journal Title
Journal ISSN
Volume Title
Publisher
IMed Research Publications
Abstract
Background: Intravenous fluid and electrolyte therapy in most of the acutely ill hospitalized children has beenthe cornerstone of medical practice for a well over 50 years.Objective: To determine optimal maintenance fluid therapy by comparing the incidence of hyponatremia orhypernatremia in hospitalised children.Methods: A prospective Randomized study done in PICU in patients admitted to paediatric emergency. The studywas conducted between September 2007 to May 2008. Children of age group 1 month to 16 years were included.The fluid groups were divided into four groups. SPSS version 18 was used for analysis.Results: The mean age in group I is 4.42, in group 2 is 3.84, in group 3 is 3.67 and in group 4 is 4.45. The meanserum sodium levels in fluid group 1 is 137.4 mmol/L, in fluid group II 138.2 mmol/L, in fluid group III is 138.9mmol/L and fluid group IV is 137.8 mmol/L. After initiating maintenance fluid therapy serum sodium levelschanged in each group. As we can see in group 1 mean serum sodium level at the start of the therapy is 137.43mmol/L and after 24 hours of hypotonic fluid infusion it reduced to 135.4 mmol. 69 patients had hyponatremiaand 44 had hypernatremia.Conclusion: Amount of free fluid in the IV maintenance fluid can be factor in causing hypernatremia. Caution iswarranted to guard off a rapid fall of serum sodium level.
Description
Keywords
Hyponatremia, Hypernatremia, electrolytes, PICU
Citation
Koonwar Sciddhartha, Azad Kanchan Lata, Kumar Sarvesh, Kumar Rashmi. Acute Hyponatremia And Hypernatremia Related To Intravenous Fluid Administration In Hospitalized Children: A Randomized Observational Study. International Journal of Integrative Medical Sciences. 2019 Apr; 6(4): 821-825