Study of Anaemia and Iron Profile in the Subjects with Vitamin D Deficiency Comparison with Healthy Controls without Vitamin D Deficiency
Loading...
Date
2019-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
International Society for Contemporary Medical Research
Abstract
Introduction: Iron and vitamin D are two essential nutrientswhich constitute an important worldwide health issue dueto their significant roles in biochemistry. The present studywas conducted to assess the prevalence and risk of anemiain a population of subjects with documented D25 deficiencycompared with those with normal D25 levels.Material and Methods: The present case control study wasconducted among 100 subjects (50 were cases and 50 werecontrols) in the department of Medicine at Chattrapati ShivajiSubharti Hospital. Total serum 25(OH)D concentrationwas analyzed using commercially available ELISA kits.According to the manufacturer’s instructions, concentrationsof 25(OH)D below 25 nmol/L were classified as a deficiency,and values of 25–75 nmol/L were considered a vitamin Dinsufficiency. Difference between two groups was determinedusing chi square test and student T test for categorical data andcontinuous data respectively. P-value of <0.05 was consideredas significant.Results: Hb<13 was found in 75% of the case group (male)and 25% of the control group (male). Hb<12 was found in64.29% of the case group (female) and 45.45% of the controlgroup (female). Mean iron (μg/dl) among the male and femalecase group was less as compared to the control group withstatistically significant difference as p<0.05.Conclusions: The results of the present study showed thatVitamin D metabolism is dependent on iron and its deficiencymight disturb Vitamin D activation
Description
Keywords
Vitamin D, Iron, Anemia, Deficiency
Citation
Vikki, Kumar Amit, Akshita. Study of Anaemia and Iron Profile in the Subjects with Vitamin D Deficiency Comparison with Healthy Controls without Vitamin D Deficiency. International Journal of Contemporary Medical Research . 2019 Dec; 6(12): l4-l8