Human Immunodeficiency Virus and Human papillomavirus in Immunopathology of Cervical Cancer

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Date
2019-11
Journal Title
Journal ISSN
Volume Title
Publisher
International Society for Contemporary Medical Research
Abstract
The field of cancer immunobiology has been fast expanding.The realms of cervical cancer and immunodeficiency interactingat the molecular level has been actively investigated. The roleof the Human papillomavirus and developement of cervicalcancer admist a background of immunodeficiency is reviewedfor the novelty of the interaction between the HPV inducedoncogenesis and the host cellular responses in HIV positivewomen.The review aims to revisit the subject and generateinterest and research on HPV induced oncogenesis with anultimate aim to prevent cervical cancer. Greater understandingof the molecular pathways that underlie progression of highgrade IN to invasive cancer would be of great importancein the identification of the genetic markers that are able toidentify the women who have a high risk of progression tocancer, and therefore in need of aggressive monitoring andtherapy to prevent the development of cervical cancer.
Description
Keywords
HPV, HIV, Cervical Cancer, Oncogenesis
Citation
Lall Mahima, Sen Sourav, Gupta Rajiv Mohan. Human Immunodeficiency Virus and Human papillomavirus in Immunopathology of Cervical Cancer. International Journal of Contemporary Medical Research . 2019 Nov; 6(11): k15-k17