Antibiotic sensitivity pattern of bacterial isolates from sputum samples of admitted patients with acute lower respiratory tract infections in a tertiary care teaching hospital of Tripura: a hospital record-based study
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Date
2020-02
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Background: Antibiotics are frequently used for various infectious diseases e.g., acute lower respiratory tract infection (ALRTI). But, injudicious use of antibiotics often leads to antibiotic resistance which is an emerging problem. The objective of this study was taken up to analyse the antimicrobial sensitivity pattern of pathogens isolated from the sputum samples of admitted patients suffering from ALRTI in a tertiary care teaching hospital.Methods: It is a hospital record-based study with a sample size of 393.Results: Klebsiella (52.16%) was the most common organism followed by Acinetobacter (13.49%) and Pseudomonas (13.23%) isolated from the sputum sample. Imipenem, piperacillin/tazobactam combination and gentamicin was sensitive against Klebsiella and Pseudomonas and the association were statistically significant. Acinetobacter was resistant to ceftriaxone.Conclusions: The commonest pathogens isolated from the sputum samples were Klebsiella followed by Acinetobacter and Pseudomonas. Imipenem, piperacillin/tazobactam combination and gentamicin was sensitive against Klebsiella and Pseudomonas.
Description
Keywords
Antibiotic resistance, Klebsiella, Acinetobacter, Lower respiratory tract infection
Citation
Debnath Shubhaleena, Bhaumik Debasree, Chakraborty Maitrayee, Ghosh Ranjib, Das Lakshman, Bhattacharjee Prithul. Antibiotic sensitivity pattern of bacterial isolates from sputum samples of admitted patients with acute lower respiratory tract infections in a tertiary care teaching hospital of Tripura: a hospital record-based study. International Journal of Basic & Clinical Pharmacology. 2020 Feb; 9(2): 254-258