Methotrexate induced ventricular arrhythmia as a medication error: a case report
Loading...
Date
2019-09
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Methotrexate (MTX) is the most widely used drug in clinical practice for long term treatment of connective tissue disorders. As this drug has narrow therapeutic index, if it goes unmonitored can lead to life threatening complications. Herein we are describing the case of a patient who presented with ventricular arrhythmia, due to failure to execute MTX therapy in the prescribed frequency and took daily dose of MTX which was meant to be taken as a weekly dose pointing to failure of patient education or patient comprehension regarding MTX and finally succumbed due to cardiogenic shock. We concluded this causality as probable/likely category according to WHO-UMC causality categories.
Description
Keywords
Methotrexate toxicity, Mucositis, Ventricular arrhythmia
Citation
Shah Shailja S., Gupta Sapna, Vala Jasvin, Malhotra Supriya D., Patel Pankaj. Methotrexate induced ventricular arrhythmia as a medication error: a case report. International Journal of Basic & Clinical Pharmacology. 2019 Sep; 8(9): 2163-2166