An observational study on the surgical antibiotic prophylaxis in the surgery ward of a tertiary care hospital
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Date
2019-07
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Background: Surgical site infection (SSI) is the most common postoperative complication and represents a significant burden in terms of patient morbidity, mortality and cost to health services around the world. Appropriate antibiotic prophylaxis helps in reducing the incidence of SSIs. Appropriate surgical prophylaxis is a multifactorial process that depends on proper case selection, antibiotic selection including dosing and route of administration and duration of therapy.Methods: A prospective observational study was conducted over 3 months on 200 operated patients in surgery ward of a tertiary hospital. Patient details like demography, type of surgery performed and antibiotics prescribed pre and post-surgical procedure was collected and analysed using Microsoft excel.Results: Out of 200 patients 32.5% (65) were females and 67.5% (135) were males. Total number of prophylactic antibiotics prescribed were 368. The most commonly prescribed group of antibiotics was cephalosporins (44.29%) followed by metronidazole (26.5%) and ofloxacin (9.48%). Among the cephalosporins the most commonly prescribed was cefuroxime in 82 patients (50.3%) and cefoperazone in 79 patients (48.46%). SSI developed in 3 out of 200 patients (1.5%).Conclusions: There is an urgent requirement to promote rational antibiotic prescribing among surgeons. The need of the hour is developing and implementing national guidelines for surgical prophylaxis by a multidisciplinary group of experts.
Description
Keywords
Surgical prophylaxis, Surgical site infection, Antibiotic prescribing, Surgery
Citation
Kudchadkar Aditi A., Bhounsule Sushama A.. An observational study on the surgical antibiotic prophylaxis in the surgery ward of a tertiary care hospital. International Journal of Basic & Clinical Pharmacology. 2019 Jul; 8(7): 1647-1651