Efavirinz induced gynecomastia: a case report

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Date
2019-02
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Gynecomastia is swelling of the breast tissue in men, caused by an imbalance of the hormones, estrogen and testosterone. Drugs commonly implicated are spironolactone, cimetidine, ketoconazole, hGH, estrogens, hCG, anti-androgens, GnRH analogues and 5-? reductase inhibitors. Medications probably associated with gynecomastia include risperidone, verapamil, nifedipine, omeprazole, alkylating agents, HIV medications (efavirenz), anabolic steroids, alcohol and opioids. HIV infected patients who are treated with highly active antiretroviral therapy (HAART) can develop breast enlargement due to benign and malignant mammary diseases. We report here a case of gynecomastia due to efavirinz.
Description
Keywords
Efavirinz, Gynecomastia, HAART
Citation
M. D. Jayalakshmi, Torvi Janaki R.. Efavirinz induced gynecomastia: a case report. International Journal of Basic & Clinical Pharmacology. 2019 Feb; 8(2): 351-353