Neonatal Mucormycosis with Gastrointestinal and Cutaneous involvement

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Date
2018-05
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Academy of Pediatrics
Abstract
Background: Mucormycosis of the gastrointestinal tract is a rare fungal infection ofneonates. Case characteristics: 48-hours-old term neonate presented with intestinalobstruction and perforation. No significant risk factors were present. Histopathologicalexamination of the resected gangrenous bowel revealed mucormycosis. Cutaneousinvolvement due to systemic spread led to dermal necrosis in toes. Outcome: Thoughcutaneous lesions responded promptly to antifungal therapy, gastrointestinalmanifestations required multiple antifungal therapy for prolonged period apart from surgicaldebridement. Message: Precise histopathological diagnosis and early appropriate therapycan prevent dismal outcomes in neonatal mucormycosis.
Description
Keywords
Gangrene, Intestinal perforation, Necrotizing enterocolitis, Neonate.
Citation
Devi R Usha, Balachandran Anitha, Kamalarathnam CN, S Pappathi. Neonatal Mucormycosis with Gastrointestinal and Cutaneous involvement. Indian Pediatrics. 2018 May; 55(5): 427-428