Relative potency of different generic brands of meropenem, colistin and fosfomycin: Implications for antimicrobial therapy and antimicrobial formulary

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Date
2019-03
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Association of Medical Microbiologists
Abstract
There is a need of a relatively simple and inexpensive method for the determination of relative potency of various generic brands of antibiotics in comparison to original products. The current study describes an agar diffusion method which can be performed in any microbiology laboratory, is cheap (costs $2 per test) and its results can be available after overnight incubation. The results show that neither all generics are reliable nor are all generic antibiotics of poor quality.
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Keywords
Agar diffusion, colistin, fosfomycin, generic brands, meropenem, relative potency
Citation
Das P, Jana B, Dhar K, Goel G, Bhattacharya S, Chandy M. Relative potency of different generic brands of meropenem, colistin and fosfomycin: Implications for antimicrobial therapy and antimicrobial formulary. Indian Journal of Medical Microbiology. 2019 Mar; 37(1): 95-98