Herpes simplex virus type 2 and cytomegalovirus perigenital ulcer in an HIV infected woman

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Date
2018-09
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Association of Medical Microbiologists
Abstract
We report a case of mucocutaneous Herpes Simplex Virus (HSV)-2 and Cytomegalovirus (CMV) infection in a 39-year-old female with acquired immunodeficiency syndrome, who presented with a perigenital ulcer. The patient was receiving antiretroviral treatment (ART) for 3 months before presentation. Scraping from the perigenital ulcer was positive for HSV-2 and Treponema pallidum using polymerase chain reactions (PCR). The extent and duration of the lesions led us to consider the possibility of coinfection with CMV. The patient also tested positive for CMV by PCR. On subsequent follow-up after 8 weeks, the genital lesions had healed completely. This is possibly ascribable to the ART, which led to significant immune reconstitution.
Description
Keywords
Cytomegalovirus, herpes simplex virus, human immunodeficiency virus
Citation
Rawre J, Rai M, Namdeo D, Das R, Khanna N, Dar L, Dhawan B. Herpes simplex virus type 2 and cytomegalovirus perigenital ulcer in an HIV infected woman. Indian Journal of Medical Microbiology. 2018 Sep; 36(3): 441-443