Histomorphometric changes of gonads in male guinea pigs after thymectomy
Loading...
Date
2019-10
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
IMED Research Publications
Abstract
Introduction: The presence of the thymus gland during early life is essential for the normal development ofimmune system and as well as proper maturation of the hypothalamic – pituitary- gonadal axis. This study wasto investigate the influence of thymus gland on male reproductive function.Aim: The aim of this study to investigate the effect of thymectomy on Morphometric changes of gonads inneonatal, prepubertal and pubertal thymectamized male guinea pigs.Material and Methods: In this study, a total of thirty male guinea pigs, thymectamized (n-6) and sham-operated(n-4) were studied in each group. The comparison of diameter of seminiferous tubules, luminal diameter andepithelial thickness in the thymectamized and sham operated male guinea pigs.Results: No Significant changes in the morphometry of seminiferous tubules of testis in thymectamized maleguinea pigs compared to the sham-operated guinea pigs in all age groups. These results suggest that thymectomyhad no detrimental effects on reproductive system in males at any intervals.
Description
Keywords
Thymectomy, Seminiferous diameter, Luminal diameter and Epithelial thickness
Citation
P. Murali, J. Radhika. Histomorphometric changes of gonads in male guinea pigs after thymectomy. International Journal of Anatomy and Research. 2019 Oct; 7(4): 7187-7192