A clinicopathological study of persistent fetal vasculature

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Date
2019-06
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
Purpose: To study the clinicopathological findings of Persistent Fetal Vasculature (PFV) in patients with congenital cataract and PFV. Methods: Six eyes with anterior or combined PFV with cataract underwent phacoaspiration with primary posterior capsulotomy with anterior vitrectomy with intraocular lens implantation followed by histopathological evaluation of the PFV stalk and membrane. Results: Four and two patients had combined and anterior PFV respectively. There was no postoperative hyphema, vitreous haemorrhage, glaucoma or retinal detachment in six months. Haematoxylin and eosin staining showed inflammatory cells predominantly with extramedullary hematopoeisis and vascularisation. Conclusion: We recommend IOL implantation in PFV, with early and aggressive amblyopia therapy.
Description
Keywords
Congenital cataract, histopathology of persistent fetal vasculature, persistent fetal vasculature, persistent hyperplastic primary vitreous
Citation
Khurana S, Gupta PC, Vaiphei K, Singh R, Ram J. A clinicopathological study of persistent fetal vasculature. Indian Journal of Ophthalmology. 2019 Jun; 67(6): 785-787