Leukostasis retinopathy: An uncommon visual threatening complication of chronic myeloid leukemia with severe hyperleukocytosis – A case report and review of the literature

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Date
2018-12
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
To describe a rare case of an unusual visual threatening complication of chronic myeloid leukemia (CML). A 21-year-old male visited the hospital complaining of 1-week painless binocular acute visual loss without any other symptoms. The patient was diagnosed with CML. He then received emergent leukapheresis with imatinib treatment, which achieved obvious hematological remission. However, the visual acuity did not recover along with the CML remission and ocular structure relief. CML-related leukostasis could induce severe leukostasis retinopathy. Hematologists and ophthalmologists should pay more attention to this relatively rare and severe complication of CML.
Description
Keywords
Chronic myeloid leukemia, hemorrhagic retinal detachment, leukostasis
Citation
Chen B, Yan X, Zhang X, Yang H. Leukostasis retinopathy: An uncommon visual threatening complication of chronic myeloid leukemia with severe hyperleukocytosis – A case report and review of the literature. Indian Journal of Ophthalmology. 2018 Dec; 66(12): 1871-1874