Endogenous Cryptococcus neoformans endophthalmitis with subretinal abscess in a HIV-infected man

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Date
2018-07
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
To report a rare case of Cryptococcus neoformans endogenous endophthalmitis with subretinal abscess in a 36-year-old HIV-positive man, referred with progressive blurred vision in his right eye for the last 6 months. Vitreous biopsy followed by intravitreal ganciclovir did not result in significant improvement. Microbiology revealed the presence of C. neoformans, and intravitreal amphotericin B was then administered. The patient was treated aggressively with systemic and intravitreal antifungals but had a poor visual and anatomical outcome. A high degree of clinical suspicion combined with microbiological evaluation helped to arrive at an appropriate diagnosis.
Description
Keywords
Cryptococcus, endophthalmitis, immunocompromised, subretinal abscess
Citation
Joseph J, Sharma S, Narayanan R. Endogenous Cryptococcus neoformans endophthalmitis with subretinal abscess in a HIV-infected man. Indian Journal of Ophthalmology. 2018 Jul; 66(7): 1015-1017