A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab
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Date
2018-07
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
A 42-year-old male presented to us after an episode of acute anterior human leukocyte antigen (HLA)-B27-associated uveitis, and intraocular pressure (IOP) in the right eye was 4 mmHg. Ultrasound biomicroscopy revealed ciliary body edema with supraciliary effusion. He was on a frequent topical corticosteroid, and oral steroid in addition to receiving a periocular injection depot corticosteroid 20 days back. He was started on treatment with subcutaneous golimumab (GLM). After a month, his IOP in the right eye was 14 mm of Hg with UBM showing resolution of ciliary body edema. GLM can be useful in the management of steroid-resistant cases of HLA B-27-associated ocular hypotony.
Description
Keywords
Golimumab, human leukocyte antigen B-27, ocular hypotony, ultrasound biomicroscopy
Citation
Majumder PD, Lakra R, Yamuna G, Majumder AK, Kaushik V. A case of human leukocyte antigen B-27-associated ocular hypotony successfully treated with golimumab. Indian Journal of Ophthalmology. 2018 Jul; 66(7): 1006-1008