Bilateral herpes simplex keratitis reactivation after lacrimal gland botulinum toxin injection

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Date
2018-05
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
Botulinum toxin A (BTA) injections into lacrimal gland are being used for refractory epiphora due to intractable lacrimal disorders with success rates reported from 18% to 86%. Most common side effects are transient ptosis and diplopia. We report a case of a 59-year-old female injected with 2.5 units of BTA injection in each lacrimal gland for functional epiphora. The patient had a history of herpes simplex viral keratitis that was quiescent for more than 2 years. After 3 weeks, she developed reactivation of viral keratitis bilaterally, which was successfully managed with antivirals and topical steroids. Reactivation of quiescent herpes simplex keratitis is a possibility after lacrimal gland BTA and caution should be exercised in such cases.
Description
Keywords
Botulinum toxin, functional epiphora, herpes simplex keratitis, lacrimal gland, reactivation
Citation
Narang P, Singh S, Mittal V. Bilateral herpes simplex keratitis reactivation after lacrimal gland botulinum toxin injection. Indian Journal of Ophthalmology. 2018 May; 66(5): 697-699