Reactivation of herpes simplex viral keratitis following the botulinum toxin injection

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Date
2018-02
Journal Title
Journal ISSN
Volume Title
Publisher
All India Ophthalmological Society
Abstract
We describe a case of 55-year-old male farmer presented with recurrent corneal abrasions with a spastic entropion in the left eye. Superior cornea showed typical nummular opacities suggestive resolved herpetic eye diseases. On further enquiry, he had similar episodes in the past. Contralateral eye was essentially normal. Following the botulinum toxin injection for the management of spastic entropion, subject developed reactivation of herpetic necrotizing stromal keratitis. Diagnostic corneal scrapings were negative for herpes simplex virus-1 antigen by immunofluorescence assay and for DNA by molecular techniques. The case was successfully managed with topical steroids and antiviral medications.
Description
Keywords
Botulinum toxin, herpes simplex viral keratitis, reactivation of herpes
Citation
Ramappa M, Jiya PY, Chaurasia S, Naik M, Sharma S. Reactivation of herpes simplex viral keratitis following the botulinum toxin injection. Indian Journal of Ophthalmology. 2018 Feb; 66(2): 306-308