Case Report of Non-small Cell Lung Cancer Patient with EGFR T790M Mutation Treated with Th ird Generation Inhibitor

Abstract
Lung cancer treatment based on the molecular classifi cation of the tumor has paved the way for multiple lines of targeted treatment, even though the development of resistance remains a major cause of concern. Epidermal growth factor receptor (EGFR) remains the poster boy for the use of targeted therapy, and the presence/absence of mutations in this gene has led to the development of inhibitors targeting specifi c mutations. We present the case of an advanced non-small cell lung cancer patient with EGFR T790M mutation treated with Osimertinib, a third-generation inhibitor.
Description
Keywords
Non-small cell lung cancer, T790M, Osimertinib
Citation
Doval Dinesh Chandra, Tripathi Rupal, Choudhury Kumardeep Dutta, Sharma Ajay, Batra Ullas, Mehta Anurag, Choudhury PS. Case Report of Non-small Cell Lung Cancer Patient with EGFR T790M Mutation Treated with Th ird Generation Inhibitor. Indian Journal of Medical Sciences. 2019 Jan; 71(1): 49-51