Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report
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Date
2020-02
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Association of Pathologists and Microbiologists
Abstract
Malignant phyllodes tumor of the prostate is a very rare entity. Here, we describe a 51-year-old patient with a malignant phyllodes tumor of the prostate with a poor prognosis and normal prostate-specific antigen levels. Digital rectal examination revealed a hard, nodular mass in the prostate, and magnetic resonance imaging exhibited a cystic mass measuring 8.7 cm × 7.0 cm × 6.7 cm. Immunohistochemical staining showed that the epithelial components were positive for CK8/18 and cytokeratin AE1/AE3; the atypical stromal cells were positive for CD34 and vimentin. Histological analysis resulted in a diagnosis of malignant phyllodes tumor of the prostate. Radical surgery was the treatment of choice. However, tumor recurrence was identified 6 months after the surgery, and the patient died 10 months after the surgery.
Description
Keywords
Immunohistochemical analysis, malignant phyllodes tumor, prostate, prostate-specific antigen
Citation
Zhang X, Hu J, Xu X, Cheng L. Rapidly progressing malignant phyllodes tumor of the prostate with normal prostate-specific antigen levels: A case report. Indian Journal of Pathology and Microbiology. 2020 Feb; 63(5): 50-52