A unique case of eyelid metastasis from chondroid chordoma

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Date
2019-06
Journal Title
Journal ISSN
Volume Title
Publisher
Indian Association of Pathologists and Microbiologists
Abstract
A unique case of eyelid metastasis from nasopharyngeal chondroid chordoma in a 63-year-old woman was reported. Chordomas are rare tumors of the bone deriving from remnants of the embryonic notochord. Histologically, the tumor showed lobulated structure and concludes two types of cells: liquid drop cell and small round/cubic cell. Immunohistochemically, AE1/AE3, epithelial membrane antigene (EMA), and S100 showed a uniform and strong positivity. It has a great capacity for recurrence and malignant transformation, despite their slow-growing nature. The most common sites of metastases are liver, lungs, and bones. The eyelid metastasis from chordoma is an extremely rare finding, which may suggest a poor prognosis for the patient. Its significant clinicopathological characteristic could prompt us to take it into consideration when assessing the patient's prognosis.
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Keywords
Chondroid chordoma, eyelid, metastasis, subcutaneous
Citation
Ren H, Zhao X, Wei N, Huang H, Li W, Li H. A unique case of eyelid metastasis from chondroid chordoma. Indian Journal of Pathology and Microbiology. 2019 Jun; 62(2): 287-289