Use of Validated Severity Scales for Measurement of Lepra Reactions

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Date
2019-03
Journal Title
Journal ISSN
Volume Title
Publisher
Hind Kusht Nivaran Sangh (Indian Leprosy Association)
Abstract
The need of a validated scale or tool to measure a disease condition, particularity its severity, cannot be over emphasized in clinical research. A validated scale can be used to compare a condition across cultures. Reactions in leprosy continue to be important causes of morbidity both systematic as well as local in the form of pain and disabilities. Measurement of their severity may be helpful in rationalizing their proper management. In this article, the salient features of validated tools to measure type 1 and 2 reactions in leprosy developed during last 7-12 years have been reviewed. The processes of validations are described too. Experience so far with the use of these severity scales to classify and monitor the anti-reaction treatment is limited. There is need to gain more experience in different endemic countries/regions so that duration and doses of anti-reaction agents could be better rationalized. Depending upon the field experience, these severity grading systems may be evolved further.
Description
Keywords
Severity scales, Lepra reactions, ENL, Leprosy
Citation
Rana DSJB, Dulal S. Use of Validated Severity Scales for Measurement of Lepra Reactions. Indian Journal of Leprosy. 2019 Mar; 91(1): 55-63