Adult onset still’s disease: a diagnostic dilemma

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Date
2019-11
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Adult onset still’s disease is a rare systemic inflammatory disorder of unknown aetiology, characterized by clinical triad (high spiking fever, evanescent rash and arthritis) and biological triad with lack of serological markers as a true gold standard makes diagnosis difficulty. Here is a case of 32year old male presented with high grade fever for 2 months, joint pains and swelling for 1month rash for 3 days. O/E: pallor and B/L tender, swollen ankle and knee joints, and P/A: splenomegaly. Investigations showed-Hb%. 8 gms, neutrophilic leucocytosis with thrombocytosis, ESR:72 mm/1h, CRP elevated. ASO-titre, RA factor and Anti CCP antibodies are negative. Adult onset still’s disease is a heterogenous and rare systemic inflammatory disorder of unknown aetiology with lack of serological diagnostic modalities.
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Keywords
Adult onset still’s disease, Arthritis, Evanescent rash, High spiking fever, Pyrexia of unknown origin
Citation
Reddy Dugganapalli Dinesh Kumar, Sindhusha Veeraballi, Jagadeesh Metta. Adult onset still’s disease: a diagnostic dilemma. International Journal of Advances in Medicine. 2019 Nov; 6(6): 1950-1952