Role of serum interleukin-6 in heart failure
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Date
2018-07
Journal Title
Journal ISSN
Volume Title
Publisher
Medip Academy
Abstract
Background: A growing body of evidence suggests that inflammation plays the key role in different cardiovascular diseases. But very study has been done so far in relation to serum interleukin-6 in heart failure patients. The aim of the study was to measure serum interleukin-6 in heart failure patients.Methods: Total 22 heart failure patients and 22 age and sex matched controls were included in this study from August 2015 to June 2016 for serum analysis of interleukin-6.Results: serum interleukin-6 was significantly [median(IQR) 14.3(26.2) pg/mL] increased in heart failure patients compared to age and sex matched controls [median(IQR) 0(2.4) pg/mL].Conclusions: Even though little is known about function of interleukin-6 in heart failure patients, this study shows that increased level of IL-6 in heart failure patients plays an important role as a pro-inflammatory marker in development of cardiovascular disease i.e. heart failure.
Description
Keywords
Cardiovascular disease, Enzyme-linked imunosorbent assay, Heart failure, Inflammatory markers
Citation
Deokar Smita Amol, Dandekar Sucheta P., Shinde Ganesh A., Prabhu Surekha S., Patawardhan Mugdha. Role of serum interleukin-6 in heart failure. International Journal of Advances in Medicine. 2018 Jul; 5(4): 936-940