Complete genome sequence analyses of an Indian cattle strain of bovine viral diarrhoea virus 2 (BVDV-2)

Abstract
Bovine viral diarrhea virus (BVDV) is a pestivirus which infects cattle worldwide causing substantial economic losses in cattle farming. BVDV is divided into two recognized species, BVDV-1 and BVDV-2 and one tentative species, BVDV-3. Since, complete genome sequence analysis can provide better insights into molecular epidemiology of BVD, we report here the first complete genome sequence analyses of an Indian BVDV-2 strain isolated from cattle. The full-genome of strain Ind 141353 contains 12285 nucleotides (nt) with a single large open reading frame which codes for 3898 amino acids. Phylogenetic analysis indicated that this strain belongs to the BVDV-2a subtype and has highest (93%) level of genetic identity with the Chinese cattle strain JZ05-1. It was inferred that although introduction from China is possible, introduction of BVDV-2 into Indian and Chinese cattle from a common trade source cannot be ruled out completely. The results in this study extend the spectrum of pestivirus molecular data and provide important insights into BVDV molecular epidemiology.
Description
Keywords
Citation
Mishra Niranjan, Behera Sthita Pragnya, Kalaiyarasu Semmannan, Nema Ram Kumar, Dubey Pooja, Rajukumar Katherukamem. Fluctuating temperature: A cause for survival and development of entomopathogenic nematodes, Heterorhabditis indica and Steinernema carpocapsae. Indian Journal of Experimental Biology. 2018 May; 56(5): 327-333