Kin Mediated Human Papillomavirus Infection In Breast: A Report Of Four Cases

Abstract
To address the ambiguity of different modes of human papillomavirus (HPV) transmission in breast, the immunohistochemical expression of two oncoproteins E6/E7 of HPV16 was analyzed in primary breast cancer (BC) and adjacent normal skin of 4 samples. The patients were of 35–55 years old having no previous history of cancer. The E6/E7 expressions were evident in both skin and BC. In skin, high/moderate cytoplasmic expressions of E6/E7 proteins were seen in all samples, whereas in BC, high/moderate cytoplasmic expressions of the proteins were observed in 2–3 samples. Thus, it seems that HPV infection in the breast may occur through the skin
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Citation
Islam Saimul, Dasgupta Hemantika, Basu Mukta, Roy Anup, Alam Neyaz, Mandal Gautam Kumar, Roychoudhury Susanta, Panda Chinmay Kumar. Kin Mediated Human Papillomavirus Infection In Breast: A Report Of Four Cases. Indian Journal of Case Reports. 2018 Mar; 4(2): 98-102