Clinicoradiological Profile of Patients with Diffuse Parenchymal Lung Disease
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Date
2019-03
Journal Title
Journal ISSN
Volume Title
Publisher
Society for Health Care & Research Development
Abstract
The profile of diffuse parenchymal lung disease (DPLD) has mainly been reported from the developed countries; the prevalence and outcome of DPLD is not studied well across India. The aim of this study is to describe the clinical radiological spectrum of various DPLDs from a tertiary care centre of a developing country. Methods: An observational cross-sectional study was carried out in a single tertiary care center in northern India which included 50 consecutive subjects (age >12 years) who had diffuse parenchymal lung diseases. In this study, the clinical, radiological and histological data subjects was collected. Results: Out of the total 50 subjects, mean age was 49.04 years with females constituting 58% of the total. Most common symptoms were gradually progressing dyspnoea (100%) followed by dry cough (76%). The commonest finding on chest radiograph in our series was reticular pattern (78%).The commonest pattern on high-resolution computed tomography was traction bronchiectasis (56%), followed by honeycombing (50%), septal thickening (46%).The commonest cause of DPLD in study was Idiopathic Pulmonary Fibrosis (38) %, followed by connective tissue – interstitial lung disease (CTD-ILD)(26%) and NSIP(12%). Smoking was one of the major risk factor associated with IPF, and 52.6% of patients with IPF were smokers (P<0.001). Conclusion: IPF (38%) was the commonest DPLD seen followed by CTD- ILD and NSIP at a tertiary center in northern India similar to the spectrum reported from developed countries. More studies are required from developing countries to ascertain the spectrum of DPLDs in different geographic
Description
Keywords
Diffuse Parenchymal Lung Disease, Idiopathic Pulmonary Fibrosis, connective tissue – interstitial lung disease (CTD-ILD)
Citation
Pandhi Naveen, Rana Srijna, Malhotra Balbir, Kajal NC, Gupta Sandeep, Neki NS, Kaur Amritpal, Randhawa Dilbag. Clinicoradiological Profile of Patients with Diffuse Parenchymal Lung Disease. Annals of International medical and Dental Research. 2019 Mar; 5(2): 33-37