Association Between Nutrition Status and Cognitive Impairment Among COPD Patients and age Matched Healthy Controls
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Date
2018-09
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Society for Health Care & Research Development
Abstract
Background:Nutritional abnormalities & Cognitive decline are frequent systemic manifestations associated with COPD. The study aimed to investigate and compare the cognitive & nutritive parameters in COPD with age matched healthy controls, and to find association between cognitive impairment & nutrition parameters. Methods: 100 subjects were recruited, and divided into two groups. Group I consisted of fifty consecutive physician diagnosed COPD patients & Group II included fifty healthy volunteers respectively. The spirometric parameters recorded were FEV1 (Liters), FVC (liters), FEV1/FVC ratio(% predicted),FEF 25%75%(liters/sec). Anthropometric measurements included Body Weight, Height and BMI measurements. Nutritional status was assessed using mini nutritional questionnaire (MNA). Body composition was assessed by four-frequency bioelectric impedance analysis (BODY STAT, QUADSCAN, USA). The following parameters were calculated: FFM, FFMI & FMI. The exercise capacity was assessed by the six minute walking distance test (6MWD). MMSE (mini mental state examination) and MOCA (montreal cognitive assessment) were used for cognitive function. All the recordings were compared within and between groups and correlation was also computed between MMSE, MOCA and MNA score. Results were analyzed using SPSS,version 16 & Pearson correlation coefficient. Results: We found out that COPD patients showed decline in all the parameters as compared to healthy controls. And, great strength of association was found between MNA & MOCA in COPD patients. Conclusion: Thus our study indicates that COPD patients have age independent loss of muscle mass as well as cognition, and loss of cognition is associated with decline in nutritional parameters or vice versa.
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Randeep Mann, Dogra Archana, Sarkar Malay, Padam Anita. Association Between Nutrition Status and Cognitive Impairment Among COPD Patients and age Matched Healthy Controls. Annals of International medical and Dental Research. 2018 Sep; 4(5): 8-12