Fungal Infections in Ear, Nose and Throat: A Clinical Study
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Date
2018-05
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Society for Health Care & Research Development
Abstract
Background: Since the beginning of medical mycology at the turn of the century there has been a continual increase in the discovery of pathogenic fungi. The morbidity and mortality associated with these infections are becoming substantial and is emerging as a public health problem. Determining the rate of infections and determining the emerging pathogen and its potential risk factors will have an important influence on the prevention and control of these fungal diseases. Data regarding these is almost non-existent for the north-eastern part of the country. Aim: The present study was done to study the pattern of fungal infections in the north-eastern India in terms of clinical parameters and required diagnostic techniques. Methods: An observational cross-sectional study was done in which all the patients who attended the Otorhinolaryngology Department of Jawaharlal Nehru Institute of Medical Sciences,Imphal during the period of August 2015 to July 2017 with features suggestive of fungal infections were included. The exclusion criteria consisted of patients suffering from malignancies and receiving radiotherapy or chemotherapy. A detailed history was taken by using a structured, open interview schedule which had sections on socio-demography and case-history. Then, all the patients were given a thorough clinical examination followed by routine laboratory investigations, radiological examination and endoscopic examination wherever indicated. Further, the study subjects underwent mycological investigations. Data collected were analysed and presented descriptively. Results & Conclusion: 80 eligible study-subjects participated in the study (58 ear, 15 throat and 7 nose & PNS cases). Otomycosis was found to be more common in the 2nd to 3rd decades of life (56.9%) and aspergillosis of nose & PNS being more common in the 2nd decade of life (42.85%) whereas oral and oropharyngeal candidiasis was more common in older age-groups (40%). In the overall, there was a male preponderance (M:F=1.15:1). Otomycosis which was mainly due to infection with A. niger had a definite relation with warm and humid climatic condition. A. fumigatus was responsible for majority of nose & PNS infections while C. albicans was the commonest fungus responsible for fungal infection of the throat.
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Citation
Karam Monica, Victor Rajkumar, Singh H. Kulabidhu. Fungal Infections in Ear, Nose and Throat: A Clinical Study. Annals of International medical and Dental Research. 2018 May; 4(3): 1-4