Correlation between Pretherapeutic Clinical and Radiological Staging of Laryngeal Malignancy: A Clinico - Radiological Study

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Date
2018-01
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Society for Health Care & Research Development
Abstract
Background: The aim of the study was to find out the correlation between pretherapeutic clinical and radiological staging of carcinoma larynx. Methods: This was a prospective cross sectional study carried out in department of ENT at Government Medical College & Dr. Susheela Tiwari government hospital, Haldwani during the period of September 2015 to 2016. 50 adult patients (mainly 4th, 5th, 6th,7th decade) having complaints of hoarseness, throat pain, neck mass etc were subjected to clinical evaluation.. Provisional clinical diagnosis of laryngeal mass was made followed by diagnostic rigid 90 degree laryngoscopy in OPD setting. It was followed by FNAC in cases of lymph node swelling. Radiological evaluation was done using CECT scan neck and MRI ( if required). Biopsy of suspected cases (malignant) was done under local or general anesthesia. Pretherapeutic clinical staging was done in patients diagnosed with carcinoma. Using information from CT and MRI pretherapeutic radiological staging was done and these patients were included in the study. Patients having benign neoplasm, lymphoma, recurrent malignant disease and those having undergone radiotherapy were excluded from the study. Comparison between pretherapeutic clinical and radiological staging of carcinoma larynx was done and its impact on treatment options was analyzed during follow up of patients. Results: It was observed in the present study that Carcinoma larynx is a male dominant disease mainly seen in elderly age group with mean age group of 65years consuming alcohol along with habit of smoking. Maximum number of cases were of supraglottic malignancy followed by involvement of glottis with no case of subglottic malignancy. In the present study we found that 32% of cases showed upstaging with CT scan, as a result of deep tumor extent undetectable at clinical examination.Conclusion:Clinical or endoscopic evaluation fails to identify invasion of the laryngeal framework and of extralaryngeal soft tissues in a high percentage of cases. An additional radiologic examination, either CT or MR imaging, is essential in most laryngeal carcinomas for the correct pretherapeutic staging and proper treatment.
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Keywords
Clinical staging, Radiological staging
Citation
Geeta, Pant Bhawana. Correlation between Pretherapeutic Clinical and Radiological Staging of Laryngeal Malignancy: A Clinico - Radiological Study. Annals of International medical and Dental Research. 2018 Jan; 4(1): 20-24