Liver dysfunction in malaria – An observational study
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Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Educational Society for Excellence
Abstract
Introduction: Malaria is associated with significant mortality and morbidity in India. Hepatic dysfunction in malaria is often under-diagnosed. Early identification of hepatic dysfunction is crucial for preventing complications. Materials and methods: A prospective observational study was conducted in NRI Medical College and General Hospital, Chinakakani, Guntur District in Andhra Pradesh. A total of 50 patients with malaria were studied. Liver function tests were performed to assess the type of jaundice. The collected data was analysed. Results: The incidence was P. Vivax and P. falciparum malaria were 64% and 34% respectively. The incidence of jaundice was 26%. All of them had predominantly conjugated hyperbilirubinemia. Around 14% had mixed jaundice, and 22% had hepatic jaundice. Only one case expired which had the highest level of serum bilirubin. Conclusion: Hepatic involvement is more common among those with malaria. The incidence in vivax and falciparum malaria is comparable. Conjugated bilirubinemia with elevated liver enzymes is the most common manifestation. Early screening and identification of hepatic involvement in malaria are crucial. Initiation of treatment on time will aid in reducing mortality and morbidity
Description
Keywords
Malaria, P vivax, P falciparum, Liver dysfunction
Citation
Vasa Vijaya Kumar, Rao Thadiparthi Murali Venkateswara, Paturi Nishanth, Penumatsa Karthik Varma, Haranadh Chintada. Liver dysfunction in malaria – An observational study. International Archives of Integrated Medicine. 2019 Apr; 6(4): 150-155